Tower climbing exercise with high-protein snack improves bone mass in Glucocorticoid-injected osteoporotic rats

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URI http://shark.lib.kagawa-u.ac.jp/kuir/metadata/1322
Title
Tower climbing exercise with high-protein snack improves bone mass in Glucocorticoid-injected osteoporotic rats
Title Alternative
タワークライミング運動と高蛋白質間食はグルココルチコイド投与による骨減弱ラットの骨量を改善する
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Description

We examined the effects of a voluntary resistance exercise (climbing) together with high-protein snacks (60% prottin) on bone mass in rats given glucocorticoid-injections (2 mag/kg/day) as a model of age-related osteopenia. Fifty-two male Sprague-Dawley rats, 8 weeks age, were assigned to exercise or sedentary groups. These groups were further divided into groups that received no snack, snack during activity or a snack during rest. All groups were meal-fed 7:30-8:30 h and 19:30-20:30 h and the snack was fed 23:30-0:30 h (active) or 11:30-12:30 h (resting). Energy and protein intake were approximately equal in all groups. The exercise groups were allowed to climb a wire-mesh tower cage ( 20 cm× 200 cm) to drink water from a bottle set at the top. Weight gain during the 8-week experimental period was inhibited by a glucocorticoid-injection. Bone mass and strength were increased by climbing exercise with a high-protein snack, while no synergistic effect of exercise and snack nor any effect of snack timing was observed. Bone weight, calcium content and protein content were positively correlated to maximum load or structural stiffness. These results suggest that resistance exercise and high-protein supplementation may be a preventive therapy for osteoporosis associated with aging.

Author
著者 Matsuo Tatsuhiro
著者(ヨミ) マツオ タツヒロ
著者(別表記) 松尾 達博
Publication Title
香川大学農学部学術報告
Volume
56
Start Page
15
End Page
22
Publisher
香川大学農学部
Published Date
20040315
ISSN
0368-5128
NCID
AN00038339
Resource Type
Departmental Bulletin Paper
Language
eng
Text Version
publisher
Set
香川大学
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