Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients

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URI http://shark.lib.kagawa-u.ac.jp/kuir/metadata/27889
Title
Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients
File
Description

Abstract
PURPOSE:

This study aimed to evaluate esophageal function before and after antireflux surgery (ARS) in neurologically impaired (NI) patients using 24 h multichannel intraluminal impedance (MII)-pH measurement.
METHODS:

Seven NI patients (age, 0-33 years; median, 13 years) were assessed before and after ARS using 24 h MII-pH. We described reflux parameters such as pH reflux index, bolus exposure index, number of acidic and nonacidic reflux episodes, mean acid clearance time and median bolus clearance time, and esophageal motility parameters in dry swallows such as bolus presence time (BPT), total bolus transit time (TBTT), and total propagation velocity (TPV).
RESULTS:

The postoperative reflux parameters such as pH reflux index, acid clearance time, bolus exposure index, and the number of acidic reflux episodes significantly decreased (P < 0.05) compared with the preoperative ones. The esophageal motility parameters including all sites of BPTs, TBTT, and TPV did not change in the MII-pH measurement after ARS (P = non-significant).
CONCLUSION:

ARS effectively reduced gastro-esophageal reflux (GER) in NI patients without the impairment of esophageal motility by MII-pH measurement. MII-pH was useful to detect the subtype of GER before and after ARS and appeared to be appropriate for evaluating esophageal motility.

KEYWORDS:

Antireflux surgery; Esophageal motility; Gastro-esophageal reflux; Multichannel intraluminal impedance-pH measurement; Neurologically impaired patients

(医博乙278)

Author
著者 田中 彩
著者(ヨミ) タナカ アヤ
著者(別表記) Tanaka Aya
Publication Title
Pediatric Surgery International
Publication Title Alternative
Pediatr Surg Int.
Volume
31
Issue
10
Start Page
911
End Page
916
Publisher
Asian Association of Paediatric Surgeons
Japanese Society of Pediatric Surgeons
Society of Pediatric Surgical Research
Pediatric Colorectal Society
Springer
Publisher Aalternative
日本小児外科学会
Published Date
2015-08-19
ISSN
0179-0358
NCID
AA1068249X
PMID
26285892
DOI
10.1007/s00383-015-3768-y
Resource Type
Thesis or Dissertation
Language
eng
Relation
出版社版DOIリンク(URL) : https://doi.org/10.1007/s00383-015-3768-y
Text Version
ETD
Grant ID
博乙第278号
Grant Date
2016-12-21
Degree Name
博士(医学)
Grantor
香川大学
Set
香川大学
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