In vivo Electron Paramagnetic Resonance Tooth Dosimetry:Dependence of Radiation-induced Signal Amplitude on the Enamel Thickness and Surface Area of ex vivo Human Teeth

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URI http://shark.lib.kagawa-u.ac.jp/kuir/metadata/28444
Title
In vivo Electron Paramagnetic Resonance Tooth Dosimetry:Dependence of Radiation-induced Signal Amplitude on the Enamel Thickness and Surface Area of ex vivo Human Teeth
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Description

Abstract

In vivo L-band electron paramagnetic resonance tooth dosimetry is a newly developed and very promising method for retrospective biodosimetry in individuals who may have been exposed to significant levels of ionizing radiation. The present study aimed to determine the relationships among enamel thickness, enamel area, and measured electron paramagnetic resonance signal amplitude with a view to improve the quantitative accuracy of the dosimetry technique. Ten isolated incisors were irradiated using well-characterized doses, and their radiation-induced electron paramagnetic resonance signals were measured. Following the measurements, the enamel thickness and area of each tooth were measured using micro-focus computed tomography. Linear regression showed that the enamel area at each measurement position significantly affected the radiation-induced electron paramagnetic resonance signal amplitude (p < 0.001). Simulation data agreed well with this result. These results indicate that it is essential to properly consider enamel thickness and area when interpreting electron paramagnetic resonance tooth dosimetry measurements to optimize the accuracy of dose estimation.

(医博甲673)

Author
著者 馬越 通崇
著者(ヨミ) ウマコシ ミチタカ
著者(別表記) Umakoshi Michitaka
Publication Title
Health Physics
Publication Title Alternative
Health Phys.
Volume
113
Issue
4
Start Page
262
End Page
270
Publisher Aalternative
Health Physics Society
Lippincott, Williams & Wilkins
Published Date
2017-10-01
ISSN
0017-9078
NCID
AA00662510
PMID
28796750
DOI
10.1097/HP.0000000000000698
Resource Type
Thesis or Dissertation
Language
eng
Relation
出版社版DOIリンク(URL): https://doi.org/10.1097/HP.0000000000000698
Resource URL
https://doi.org/10.1097/HP.0000000000000698
Rights
DOI: https://doi.org/10.1097/HP.0000000000000698
Text Version
ETD
Grant ID
博甲第673号
Grant Date
2017-09-27
Degree Name
博士(医学)
Grantor
香川大学
Set
香川大学
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