Retinal Oximetry in a Healthy Japanese Population

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URI http://shark.lib.kagawa-u.ac.jp/kuir/metadata/28493
Title
Retinal Oximetry in a Healthy Japanese Population
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Description

Abstract
PURPOSE:

To establish the normative database of retinal oximetry using Oxymap T1 in a healthy Japanese population, and study the reproducibility of the measurements in Japanese.
METHODS:

We measured oxygen saturation in the major retinal vessels with Oxymap T1 in 252 eyes of 252 healthy Japanese subjects. Fundus images acquired using Oxymap T1 were processed using built-in Oxymap Analyzer software. Reproducibility of retinal oximetry was investigated using 20 eyes of 20 healthy subjects.
RESULTS:

The mean retinal oxygen saturation of 4 quadrants in healthy Japanese was 97.0 ± 6.9% in arteries and 52.8 ± 8.3% in veins. The mean arteriovenous difference in oxygen saturation was 44.2 ± 9.2%. Both arterial and venous oxygen saturation were significantly lower in the temporal side of the retina, especially in the temporal-inferior vessels. However, the arteriovenous difference in oxygen saturation was limited in the 4 quadrants. Interphotograph, intervisit, and interevaluator intraclass correlation coefficients were 0.936-0.979, 0.809-0.837, and 0.732-0.947, respectively. In the major retinal arteries, oxygen saturation increased with age (r = 0.18, p<0.01), at a rate of 0.67% per 10 years. However, venous oxygen saturation showed no correlation with age.
CONCLUSIONS:

This study provides the normative database for the Japanese population. The arterial saturation value appears to be higher than other previous studies. Mean retinal oximetry in 4 quadrants with Oxymap T1 has high reproducibility.

Author
著者 中野 裕貴
著者(ヨミ) ナカノ ユウキ
著者(別表記) Nakano Yuki
Publication Title
PLoS ONE
Volume
11
Issue
7
Start Page
e0159650
End Page
e0159650
Publisher
Public Library of Science
Published Date
2016-07-19
ISSN
[ESSN]1932-6203
PMID
27434373
DOI
10.1371/journal.pone.0159650
Resource Type
Thesis or Dissertation
Language
eng
Relation
出版社版DOIリンク(URL) : https://doi.org/10.1371/journal.pone.0159650
PMCID:PMC4951009
Rights
出版社の著作権ポリシーにより、論文の本文は、「クリエイティブ・コモンズ 表示 4.0 国際 ライセンス」(CC-BY 4.0)で提供されます。 / Depending on the copyright policy of the publisher, the body of the paper is provided in Creative Commons Attribution 4.0 international license (CC-BY 4.0).
著者は著作権を保持します。 / Authors retain copyright
Text Version
ETD
Grant ID
博甲第683号
Grant Date
2018-03-24
Degree Name
博士(医学)
Grantor
香川大学
Set
香川大学
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